Homocysteine is a thio-containing amino acid produced by the intracellular demethylation of methionine. Total Homocysteine (Hcy) represents the sum of all forms of Hcy including forms of oxidized, protein bound and free. Elevated levels of Hcy have emerged as an important risk factor in the assessment of cardiovascular disease. Excess Hcy in the blood stream may cause injuries to arterial vessels due to its irritant nature, and result in inflammation and plaque formation, which may eventually cause blockage of blood flow to the heart.

Biorex Diagnostics manufactures Homocysteine reagents designed for Hitachi 917, Olympus AU600/400/640/2700 and CA 180/280/400 Furuno/Daytona systems.